Welcome to RevGenUK

The John Innes Centre (JIC) is at the forefront of reverse genetics through its establishment of TILLING and de-TILLING technologies in model legumes. Reverse genetics involves making a change to a specific gene, seeing what effect this has, and so working out the gene’s normal function.  We aim to develop these into a biological and bioinformatics resource for the wider plant scientific community via the RevGenUK project, providing an integrated reverse genetics platform for model plants. 

RevGenUK aims to be "A 'single-stop' shop for use in functional genomics research consisting of an efficient, self-sustaining, extendable service for reverse genetics."

It will consist of:

1. EMS and ecotype populations, with their corresponding DNA libraries, of Lotus japonicus, Medicago truncatula and Brassica rapa for TILLING and Eco-TILLING
2. A robust user-friendly plant, seed and mutant database as a web-accessible information source
3. Currently (Spring 2011), TILLING is available in L. japonicus 'Gifu' and 'MG20', M. truncatula 'Jemalong A17' and B. rapa 'R-o-18'.